Append Query Where Clause Issue

I need to append data from Table 2 into Table 1 where the Name and RefID fields in Table 2 have different values to the same fields in Table 1.

Does this make sense?

Ok, more clarification. I have a load of employees in a table (Table 1) They have the fields UniqueID, RefID, and Name. All links go through UniqueID, the name field has duplicates, and the RefID is the internal employee number and can be null where the 'employee' is a contractor.

Now, I have been handed an updated copy of that table (Table 2) in a spreadsheet. I need to load in all the records that are new in the spreadsheet to Table 1. The awkward part is that there is no uniqueID in Table 2. I cannot delete and reload all because i need to retain the original UniqueIDs in table 1 as they have linked data based on those IDs.

Can someone tell me how I can identify the new records in table 2 and then upload them to table 1.

Cheers guys and girls