Connecting To An SQL Database

I have a file called upload.vb and I am having a lot of trouble figuring out how to connect to a database that I have created in my App_Data folder called myDatabase.mdf. Here is the code on for upload.vb Imports System
Imports System.Data
Imports System.Configuration
Imports System.Web
Imports System.Web.Security
Imports System.Web.UI
Imports System.Web.UI.WebControls
Imports System.Web.UI.WebControls.WebParts
Imports System.Web.UI.HtmlControls
Imports System.IO
Imports System.Data.SqlClient

''' <summary>
''' Upload handler for uploading files.
''' </summary>
'''

Public Class Upload
Implements IHttpHandler, IReadOnlySessionState

Public Sub New()
End Sub

#Region "IHttpHandler Members"

Public ReadOnly Property IsReusable() As Boolean Implements System.Web.IHttpHandler.IsReusable
Get
Return True
End Get
End Property

Public Sub ProcessRequest(ByVal context As HttpContext) Implements IHttpHandler.ProcessRequest

If context.Request.Files.Count > 0 Then
' get the applications path
Dim tempFile As String = context.Request.PhysicalApplicationPath
' loop through all the uploaded files
Dim j As Integer = 0
While j < context.Request.Files.Count
' get the current file
Dim uploadFile As HttpPostedFile = context.Request.Files(j)
' if there was a file uploded
If uploadFile.ContentLength > 0 Then

uploadFile.SaveAs(String.Format("{0}{1}{2}", tempFile, "Uploads", uploadFile.FileName))

End If
System.Math.Max(System.Threading.Interlocked.Increment(j), j - 1)
End While
End If
' Used as a fix for a bug in mac flash player that makes the
' onComplete event not fire
HttpContext.Current.Response.Write(" ")
End Sub

#End Region

End Class Everytime I attempt to create a database connection I get all kinds Compiler errors. If anybody can help me understand how to connect to my database from this page I would greatly appreciate it. Thanks.